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A systemic, sometimes fatal reaction with airway obstruction and circulatory collapse is ________.


A) delayed
B) T-cell mediated
C) atopic
D) antibody mediated
E) systemic anaphylactic

F) A) and B)
G) B) and E)

Correct Answer

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Any heightened or inappropriate immune response resulting in tissue damage is called a(n) ________.


A) autoimmune disease
B) immunodeficiency
C) hypersensitivity
D) transfusion reaction
E) desensitization

F) All of the above
G) A) and E)

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Fungal spores and animal dander are considered to be which type of allergen?


A) Ingestant
B) Inhalant
C) Injectant
D) Contactant
E) None of the choices are correct.

F) A) and E)
G) A) and D)

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After further investigation, it is learned that the father is Rh+, and so was the first child. The patient declines the RhoGAM injection, stating "there were no complications with my first pregnancy and delivery, how can you be sure there will be with this one?" She explains how unpleasant the RhoGAM injection was with her first pregnancy, and she would like to avoid it, if at all possible. What is the most appropriate response by the nurse?


A) Because you received RhoGAM with your first pregnancy, it is not necessary during this pregnancy.
B) It is important you receive your RhoGAM injection because this child will probably develop hemolytic disease of the newborn if you do not.
C) It is important that we keep you from being sensitized to Rh factor, otherwise future pregnancies will be at risk for developing hemolytic disease of the newborn.
D) You were probably sensitized to Rh factor with your first pregnancy, so the chances are decreased that this child will develop hemolytic disease of the newborn. I will ask the doctor if we can forego the injection.

E) A) and C)
F) A) and D)

Correct Answer

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A secondary acquired immunodeficiency is ________.


A) AIDS
B) adenosine deaminase (ADA) deficiency
C) DiGeorge syndrome
D) agammaglobulinemia
E) SCID

F) A) and C)
G) A) and E)

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Based on the patient's symptoms, which of the following is the most likely diagnosis?


A) Asthma
B) Hay fever
C) Seasonal allergy
D) Eczema

E) B) and D)
F) All of the above

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Atopy and anaphylaxis are hypersensitivities in the category ________.


A) type I only
B) type I and type IV
C) type IV only
D) type I, type II, and type III
E) type I, type II, type III, and type IV

F) None of the above
G) A) and E)

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During graft rejection, cytotoxic T cells of the recipient recognize and respond to foreign class I MHC receptors on the grafted cells.

A) True
B) False

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Which event occurs with the sensitizing dose of allergen?


A) Degranulation
B) Bonding of allergen to adjacent IgE binding sites on mast cells and basophils
C) Binding of IgE by the Fc region to mast cells and basophils
D) Histamine acts on smooth muscle
E) Prostaglandins cause vasodilation and increased vascular permeability

F) C) and D)
G) B) and C)

Correct Answer

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Which event is the process of releasing chemical mediators?


A) Degranulation
B) Bonding of allergen to adjacent IgE binding sites on mast cells and basophils
C) Binding of IgE by the Fc region to mast cells and basophils
D) Histamine acts on smooth muscle
E) Prostaglandins cause vasodilation and increased vascular permeability

F) A) and D)
G) A) and B)

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A

Which of the following is not a major organ that can be a target of immune complex deposition?


A) Blood vessels and skin
B) Heart and lungs
C) Brain
D) Joints
E) Kidneys

F) A) and B)
G) A) and C)

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The chemical mediator that causes prolonged bronchospasm, vascular permeability, and mucus secretion of asthmatic patients is ________.


A) prostaglandin
B) histamine
C) leukotriene
D) serotonin
E) platelet-activating factor

F) B) and E)
G) A) and B)

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Systemic anaphylaxis can quickly result in airway blockage, shock, and death.

A) True
B) False

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A chronic, local allergy such as hay fever is considered ________.


A) delayed
B) T-cell mediated
C) atopic
D) antibody mediated
E) systemic anaphylactic

F) A) and E)
G) A) and D)

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C

Type II hypersensitivities differ from type III in that ________.


A) type II hypersensitivity involves the activation of complement proteins that attack and lyse cells, whereas type III involves the formation of immune complexes causing chronic inflammation
B) type II hypersensitivity involves the formation of immune complexes causing chronic inflammation, whereas type III involves the activation of complement proteins that attack and lyse cells
C) type II hypersensitivity involves the formation of IgM antibodies that attack tissues, whereas type III involves IgE causing degranulation of mast cells
D) type II hypersensitivity involves B cells whereas type III involves the activation and sensitization of cytotoxic T cells

E) All of the above
F) B) and C)

Correct Answer

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Contact dermatitis involves ________.


A) a sensitizing and provocative dose
B) an allergen entering the skin
C) T lymphocytes secreting inflammatory cytokines
D) itchy papules and blisters
E) All of the choices are correct.

F) A) and D)
G) All of the above

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Allergic patients receiving small, controlled injections of specific allergens are undergoing ________.


A) desensitization
B) sensitization
C) tissue matching
D) degranulation
E) None of the choices are correct.

F) B) and E)
G) A) and E)

Correct Answer

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Eczema is an autoimmune disorder.

A) True
B) False

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Which of the following is not a possible symptom of type I hypersensitivity?


A) Rhinitis
B) Rashes
C) Sneezing
D) Diarrhea
E) Contact dermatitis

F) C) and D)
G) A) and E)

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E

The patient's clinical status and lab values will be closely monitored for two weeks following his transplant. If he experiences graft rejection, what type of cells will be primarily responsible?


A) T memory cells
B) Natural killer cells
C) T cytotoxic cells
D) T helper cells

E) B) and D)
F) B) and C)

Correct Answer

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