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Questions For each description of a molecule involved in lymphocyte migration in questions ,choose the lettered description (A-I) that most closely matches it. -This molecule binds chemokines CCL19 and CCL21 and is involved in naive T cell migration into interfollicular zones of lymph nodes.


A) Peripheral lymph node addressin
B) Intercellular adhesion molecule-1 (ICAM-1)
C) Very late activation antigen-4 (VLA-4)
D) E-selectin
E) P-selectin ligand
F) CCR7
G) CXCR5
H) MadCAM-1
I) Vascular cell adhesion molecule-1 (VCAM-1)

J) F) and H)
K) F) and G)

Correct Answer

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F

Which of the following is the generative lymphoid organ for T lymphocytes?


A) Bone marrow
B) Spleen
C) Lymph node
D) Thymus
E) Tonsil

F) C) and D)
G) All of the above

Correct Answer

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Questions For each description of a molecule involved in lymphocyte migration in questions ,choose the lettered description (A-I) that most closely matches it. -This molecule is expressed on activated endothelium,is a member of the immunoglobulin superfamily,and binds to b1 integrins on activated T cells.


A) Peripheral lymph node addressin
B) Intercellular adhesion molecule-1 (ICAM-1)
C) Very late activation antigen-4 (VLA-4)
D) E-selectin
E) P-selectin ligand
F) CCR7
G) CXCR5
H) MadCAM-1
I) Vascular cell adhesion molecule-1 (VCAM-1)

J) A) and I)
K) B) and I)

Correct Answer

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Questions Match each of the descriptions in questions with the appropriate name (A-M) of an anatomic feature of lymphoid tissues. -Site of least mature T cell precursors in the thymus


A) Periarteriolar lymphoid sheath
B) Thymic medulla
C) Thymic cortex
D) Parafollicular cortex of lymph node
E) Hematopoietic bone marrow
F) Afferent lymphatic
G) Efferent lymphatic
H) Marginal zone
I) Red pulp of spleen
J) White pulp of spleen
K) Epidermis
L) Dermis
M) Peyer's patch

N) A) and I)
O) I) and L)

Correct Answer

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C

Questions For each description of a molecule involved in lymphocyte migration in questions ,choose the lettered description (A-I) that most closely matches it. -This vascular addressin binds to integrins on T cells and mediates their homing to intestinal mucosa.


A) Peripheral lymph node addressin
B) Intercellular adhesion molecule-1 (ICAM-1)
C) Very late activation antigen-4 (VLA-4)
D) E-selectin
E) P-selectin ligand
F) CCR7
G) CXCR5
H) MadCAM-1
I) Vascular cell adhesion molecule-1 (VCAM-1)

J) D) and E)
K) B) and G)

Correct Answer

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Questions Match each of the descriptions in questions with the appropriate name (A-M) of an anatomic feature of lymphoid tissues. -Location of most T lymphocytes in the spleen


A) Periarteriolar lymphoid sheath
B) Thymic medulla
C) Thymic cortex
D) Parafollicular cortex of lymph node
E) Hematopoietic bone marrow
F) Afferent lymphatic
G) Efferent lymphatic
H) Marginal zone
I) Red pulp of spleen
J) White pulp of spleen
K) Epidermis
L) Dermis
M) Peyer's patch

N) E) and K)
O) L) and M)

Correct Answer

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A

Questions For each description of a molecule involved in lymphocyte migration in questions ,choose the lettered description (A-I) that most closely matches it. -The expression of this molecule is induced on endothelial cells in inflamed tissues,and it mediates rolling of T cells along the endothelial surface.


A) Peripheral lymph node addressin
B) Intercellular adhesion molecule-1 (ICAM-1)
C) Very late activation antigen-4 (VLA-4)
D) E-selectin
E) P-selectin ligand
F) CCR7
G) CXCR5
H) MadCAM-1
I) Vascular cell adhesion molecule-1 (VCAM-1)

J) F) and G)
K) A) and E)

Correct Answer

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Questions Match each of the descriptions in questions with the appropriate name (A-M) of an anatomic feature of lymphoid tissues. -Location of Langerhans cells


A) Periarteriolar lymphoid sheath
B) Thymic medulla
C) Thymic cortex
D) Parafollicular cortex of lymph node
E) Hematopoietic bone marrow
F) Afferent lymphatic
G) Efferent lymphatic
H) Marginal zone
I) Red pulp of spleen
J) White pulp of spleen
K) Epidermis
L) Dermis
M) Peyer's patch

N) I) and J)
O) E) and F)

Correct Answer

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Questions Match each of the descriptions in questions with the appropriate name (A-M) of an anatomic feature of lymphoid tissues. -Lymphoid aggregate of the mucosal immune system


A) Periarteriolar lymphoid sheath
B) Thymic medulla
C) Thymic cortex
D) Parafollicular cortex of lymph node
E) Hematopoietic bone marrow
F) Afferent lymphatic
G) Efferent lymphatic
H) Marginal zone
I) Red pulp of spleen
J) White pulp of spleen
K) Epidermis
L) Dermis
M) Peyer's patch

N) E) and F)
O) E) and G)

Correct Answer

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Questions Match each of the descriptions in questions with the appropriate name (A-M) of an anatomic feature of lymphoid tissues. -Vessels that drain lymph away from a lymph node


A) Periarteriolar lymphoid sheath
B) Thymic medulla
C) Thymic cortex
D) Parafollicular cortex of lymph node
E) Hematopoietic bone marrow
F) Afferent lymphatic
G) Efferent lymphatic
H) Marginal zone
I) Red pulp of spleen
J) White pulp of spleen
K) Epidermis
L) Dermis
M) Peyer's patch

N) B) and D)
O) C) and L)

Correct Answer

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Questions For each description of a molecule involved in lymphocyte migration in questions ,choose the lettered description (A-I) that most closely matches it. -This receptor is expressed on naive B cells and promotes their migration into lymph node follicles.


A) Peripheral lymph node addressin
B) Intercellular adhesion molecule-1 (ICAM-1)
C) Very late activation antigen-4 (VLA-4)
D) E-selectin
E) P-selectin ligand
F) CCR7
G) CXCR5
H) MadCAM-1
I) Vascular cell adhesion molecule-1 (VCAM-1)

J) C) and G)
K) A) and F)

Correct Answer

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In naive T cell recirculation,entry of the cells into peripheral lymph nodes occurs through which specialized vessel?


A) Efferent lymphatic
B) Thoracic duct
C) Central artery
D) High endothelial venule
E) Sinusoid

F) B) and E)
G) B) and C)

Correct Answer

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